HPLC determination of ritodrine hydrochloride in pharmaceutical formulations

Revanasiddappa, H. D. and Manju, B. (2003) HPLC determination of ritodrine hydrochloride in pharmaceutical formulations. Journal of Analytical Chemistry, 58 (8). pp. 775-777. ISSN 1608-3199

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Official URL: https://doi.org/10.1023/A:1025043812783


A simple, rapid, and accurate HPLC method is described for the determination of ritodrine hydrochloride (RTH) in both pure form and pharmaceutical formulations. A Hypersil Shendon ODS column with a mobile phase of dibasic phosphate buffer and acetonitrile (75 : 25) and isoxsuprine hydrochloride were used as an internal standard. The flow rate was 1 mL min--1 and the effluent was monitored at 270 nm pH 4.0. The calibration graph is linear in the range 2--30 μg mL--1. The proposed HPLC method has been successfully employed for the determination of RTH in Yutopar tablets and injection solutions.

Item Type: Article
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: LA manjunath user
Date Deposited: 07 Sep 2019 06:43
Last Modified: 07 Sep 2019 06:43
URI: http://eprints.uni-mysore.ac.in/id/eprint/7746

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