Free volume study on calcification process in an intraocular lens after cataract surgery

Ramani, R. and Parihar, J. K. S. and Ranganathaiah, C. and Awasthi, P. and Alam, S. and Mathur, G. N. (2005) Free volume study on calcification process in an intraocular lens after cataract surgery. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 75B (1). pp. 221-227. ISSN 1552-4981

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Abstract An opacified intraocular lens explanted from a patient in the postoperative period after phacoemulsification was investigated to find the cause of opacification. From the UV-visible and energy dispersive X-ray spectroscopy (EDS) measurements, the opacification in the present case seems to be due to calcification of the intraocular lens and not due to modification in the UV absorber material of the lens. The average free volume size of the intraocular lens both in unimplanted and explanted state were obtained from positron lifetime spectroscopy (PLS). Further, the combined FTIR and PLS results indicate that calcium gets into the free volume cavities of the intraocular lens matrix as a cationic moiety, may be in the form of Ca++. The small decrease in glass transition temperature of the calcified lens seems to indicate the plasticizing action of calcium ions. The present results could be of some use in the design of the intraocular lens material in which calcification would be minimum. © 2005 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2005

Item Type: Article
Uncontrolled Keywords: intraocular lens, free volume, positron lifetime, calcification, diffusion
Subjects: D Physical Science > Physics
Divisions: Department of > Physics
Depositing User: Manjula P Library Assistant
Date Deposited: 04 Sep 2019 11:22
Last Modified: 04 Sep 2019 11:22

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