Mohammadi, J. and Naik, P. R. (2008) Evaluation of hypoglycemic effect of morus alba in an animal model. Indian Journal of Pharmacology, 40 (1). pp. 15-18. ISSN 1998-3751
Full text not available from this repository. (Request a copy)Abstract
Objective: The objective of the present investigation was to evaluate the therapeutic efficacy of mulberry leaves in an animal model of diabetes. Materials and Methods: Animals were treated with mulberry leaf extract 400 mg and 600 mg/kg body weight for 35 days. Blood glucose, glycosylated hemoglobin, triglyceride, LDL, VLDL, HDL, blood urea, cholesterol, number of β cells, and diameter of the islets of Langerhans were measured at the beginning and at the end of the experiment. Results: Blood glucose level and other parameters (except HDL) were elevated in the diabetic group, but were brought to control group level in the diabetic group treated with 600 mg/kg body weight of mulberry leaf extract. The diameter of the islets and the number of β cells were reduced in the diabetic group; both parameters were brought to control group level after treatment with mulberry leaf extract. Conclusion: Mulberry leaf extract, at a dose of 600 mg/kg body weight, has therapeutic effects in diabetes-induced Wistar rats and can restore the diminished β cell numbers.
| Item Type: | Article |
|---|---|
| Depositing User: | Users 18 not found. |
| Date Deposited: | 03 Sep 2019 05:33 |
| Last Modified: | 03 Sep 2019 05:33 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/7469 |
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