Synthesis and characterization of new diketone analogues of podophyllotoxin

Hemakumar, K. H. and Sathisha, A. D. and Basavaraju, Y. B. (2008) Synthesis and characterization of new diketone analogues of podophyllotoxin. E-Journal of Chemistry, 5 (1). pp. 114-119. ISSN 2090-9810

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Official URL: http://dx.doi.org/10.1155/2008/314724

Abstract

The new compounds 6,6a-dihydro-2,3-dimethoxy-9-nitro–11bH benzo [C]-fluoren 5,7-dione, 6,6a-dihydro-2,3-dimethoxy-9-chloro–11bH benzo[C]-fluoren-5,7-dione and 6,6a-dihydro-2,3-dimethoxy-9-fluoro–11bH benzo[C]-fluoren-5,7- dione were synthesized in high yields. They are analogues of naturally occurring lignan podophyllotoxin which exhibits anticancer activity. They are very essential to study anticancer activity.

Item Type: Article
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: Manjula P Library Assistant
Date Deposited: 30 Aug 2019 08:02
Last Modified: 30 Aug 2019 08:02
URI: http://eprints.uni-mysore.ac.in/id/eprint/7385

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