Suresha, G. P. and Prakasha, K. C. and Shiva Kumara, K. N. and Kapfo, Wethroe and Channe Gowda, D. (2009) Design and synthesis of heterocyclic conjugated peptides as novel antimicrobial agents. International Journal of Peptide Research And Therapeutics, 15 (1). pp. 25-30. ISSN 1573-3904
Full text not available from this repository. (Request a copy)Abstract
Antimicrobial peptides have been recognized as a novel class of antibiotics and several candidates are currently in clinical trials. In the present study, new antimicrobial compounds were synthesized by coupling quinazolinone moiety with the fragments of elastin sequences VP, GVP, VGVP and GVGVP. They were evaluated for their antibacterial activity against both gram positive and gram negative bacterial strains. We are here reporting that heterocyclic conjugated tetra peptide and penta peptide showed enhanced antibacterial activity compare to the conventional antimicrobial drugs.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Antimicrobial drugs; Heterocyclic conjugated peptides; Synthesis |
| Subjects: | C Chemical Science > Chemistry |
| Divisions: | Department of > Chemistry |
| Depositing User: | Users 19 not found. |
| Date Deposited: | 28 Aug 2019 06:05 |
| Last Modified: | 14 Nov 2019 10:06 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/7209 |
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