Synthesis of novel nitrogen containing naphtho[2,1-b]furan derivatives and investigation of their anti microbial activities

Nagaraja, G. K. and Prakash, G. K. and Kumaraswamy, M. N. and Vaidya, V. P. and Mahadevan, K. M. (2006) Synthesis of novel nitrogen containing naphtho[2,1-b]furan derivatives and investigation of their anti microbial activities. ARKIVOC (15). pp. 160-168. ISSN 1551-7004

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Official URL: http://dx.doi.org/10.3998/ark.5550190.0007.f19

Abstract

Ethyl naphtho[2,1-b]furan-2-carboxylate has been prepared from 2-hydroxy-1-naphthaldehyde 1 and ethyl chloroacetate, which on further treatment with hydrazine hydrate gave naphtha[ 2,1-b] furan-2-carbohydrazide 3. The resulting compound 3 was treated with substituted aldehydes of 2-chloro-3-formylquinolines to give the Schiff base, which on treatment with chloro acetyl chloride gave the title compounds. The structure of the compounds has been confirmed by elemental analysis and spectral studies. The synthesized compounds were screened for their antibacterial and antifungal activities.

Item Type: Article
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: LA manjunath user
Date Deposited: 28 Aug 2019 06:00
Last Modified: 28 Aug 2019 06:00
URI: http://eprints.uni-mysore.ac.in/id/eprint/7202

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