Base-Induced Cyclization of active methylene isocyanides with xanthate esters: an efficient method for the synthesis of 5-Alkoxy-4-(tosyl/ethoxycarbonyl)-1,3-thiazoles

Rajeev, N. and Swaroop, T. R. and Anil, S. M. and Bommegowda, Y. K. and Rangappa, K. S. and Sadashiva, M. P. (2017) Base-Induced Cyclization of active methylene isocyanides with xanthate esters: an efficient method for the synthesis of 5-Alkoxy-4-(tosyl/ethoxycarbonyl)-1,3-thiazoles. Synlett, 28 (17). pp. 2281-2284. ISSN 1437-2096

Full text not available from this repository. (Request a copy)
Official URL: https://dx.doi.org/10.1055/s-0036-1590811

Abstract

Sodium hydride-induced cyclization of 1-[(isocyanomethyl)sulfonyl]-4-methylbenzene or ethyl isocyanoacetate with various xanthate esters gave 5-alkoxy-4-tosylthiazoles or ethyl 5-alkoxythiazol-4-ylcarboxylates, respectively, in good to excellent yields. The xanthate ester S-methyl O-phenyl dithiocarbonate gave 5-(methylsulfanyl)-4-tosyl-1,3-thiazole when treated with 1-[(isocyanomethyl)sulfonyl]-4-methylbenzene under similar conditions.

Item Type: Article
Uncontrolled Keywords: thiazoles, isocyanides, xanthate esters, cyclization
Subjects: C Chemical Science > Chemistry
C Chemical Science > Organic Chemistry
Divisions: Department of > Chemistry
Depositing User: C Swapna Library Assistant
Date Deposited: 31 May 2019 04:57
Last Modified: 31 May 2019 04:57
URI: http://eprints.uni-mysore.ac.in/id/eprint/713

Actions (login required)

View Item View Item