Synthesis and pharmacological evaluation of 1,5-benzothiazepine derivatives

Kamble, Ravindra R. and Sudha, Belgur S. (2008) Synthesis and pharmacological evaluation of 1,5-benzothiazepine derivatives. Phosphorus, Sulfur, and Silicon and the Related Elements, 183 (7). pp. 1691-1709. ISSN 1563-5325

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Abstract

A simple method for the synthesis of 1,5-benzothiazepines integrated with 5-methyl-2-oxo-3-phenyl-Δ 4-1,3,4-oxadiazoles in 75–95% yield is devised. A comparison of microwave-accelerated reaction with conventional heating is also illustrated. Structures of all the newly synthesised compounds were characterised by physical, analytical and spectral (UV, IR, 1H NMR, and MS) data. Title compounds were screened for their antimicrobial, anticonvulsant, anti-inflammatory, and diuretic activities.

Item Type:	Article
Subjects:	C Chemical Science > Chemistry
Divisions:	Department of > Chemistry
Depositing User:	Manjula P Library Assistant
Date Deposited:	27 Aug 2019 06:15
Last Modified:	27 Aug 2019 06:15
URI:	http://eprints.uni-mysore.ac.in/id/eprint/7109

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