Synthesis and crystal structure of 1-(toluene-4-sulfonyl)-piperidin-4-yl-methanol

Girish, H. R. and Naveen, S. and Benaka Prasad, S. B. and Ananda Kumar, C. S. and Vinaya, K. and Sridhar, M. A. and Shashidhara Prasad, J. and Rangappa, K. S. (2008) Synthesis and crystal structure of 1-(toluene-4-sulfonyl)-piperidin-4-yl-methanol. Molecular Crystals and Liquid Crystals, 487 (1). pp. 160-169. ISSN 1563-5287

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Abstract

The title compound, 1-(toluene-4-sulfonyl)-piperidin-4-yl-methanol was synthesized by the condensation of diphenyl(piperidin-4-yl)methanol with p-toluenesulfonyl chloride in methylene dichloromethane as solvent and triethylamine as the base. The product obtained was characterized by spectroscopic techniques and the structure was investigated by X-ray crystallography. The compound crystallizes in the monoclinic crystal class in the space group P21/c with cell parameters a = 10.2490(13) A˚, b = 11.4710(9) A˚, c = 20.997(3) A˚, β = 116.344(3)°, V = 2212.2(5) A˚3 for Z = 4. The structure reveals that the piperidine ring is in a chair conformation. The geometry around the S atom is comparable with the classic tetrahedral value. The structure exhibits both inter and intramolecular hydrogen bonds of the type O–H · · · O and C–H · · · O.

Item Type:	Article
Subjects:	C Chemical Science > Chemistry
Divisions:	Department of > Chemistry
Depositing User:	Manjula P Library Assistant
Date Deposited:	27 Aug 2019 05:46
Last Modified:	27 Aug 2019 05:46
URI:	http://eprints.uni-mysore.ac.in/id/eprint/7102

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