Cytoprotective and antioxidant activity studies of jaggery sugar

Nayaka, Harish M. A. and Sathisha, U. V. and Manohar, M. P. and Chandrashekar, K. B. and Dharmesh, Shylaja M. (2009) Cytoprotective and antioxidant activity studies of jaggery sugar. Food Chemistry, 115 (1). pp. 113-118. ISSN 1873-7072

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Official URL: http://doi.org/10.1016/j.foodchem.2008.11.067

Abstract

Jaggery and other sugars namely white, refined and brown sugars were evaluated for cytoprotectivity on NIH 3T3 fibroblasts and erythrocytes, DPPH radical scavenging activity, reducing power and DNA protection. In addition, total phenol content and phenolic acid composition were also determined. Results indicated a total phenolic content of 26.5, 31.5, 372 and 3837 mu g GAE/g for refined, white, brown and jaggery, respectively. The HPLC analysis revealed the presence of different phenolic acids in brown sugar and jaggery. On NIH 3T3 cells oxidation, at 4 mg/ml concentration, jaggery showed 97% protection compared to brown sugar, and both Sugars effectively reduced erythrocyte oxidation. A dose dependent reducing power and DPPH radical scavenging activity was also observed for jaggery and brown sugar. An EC50 of 7.81 and 59.38 mu g/ml were observed for jaggery and brown sugar in the DPPH scavenging assay. In DNA oxidation studies, higher protection was observed in jaggery followed by brown, white and refined sugar treated samples. (C) 2008 Elsevier Ltd. All rights reserved.

Item Type: Article
Uncontrolled Keywords: Cytoprotective; Brown sugar; Jaggery; Reducing Power; Oxidation
Subjects: D Physical Science > Sugar Technology
Divisions: PG Centre Mandya > Sugar Technology
Depositing User: Shrirekha N
Date Deposited: 22 Aug 2019 09:46
Last Modified: 22 Aug 2019 09:46
URI: http://eprints.uni-mysore.ac.in/id/eprint/6897

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