Synthesis and anti-mildew activity of 5-(2-aroyl)aryloxymethyl-2-phenyl-1,3,4-oxadiazoles against downy mildew of pearl millet

Khanum, S. A. and Shashikanth, S. and Sudha, B. S. and Deepak, S. A. and Shetty, H. S. (2004) Synthesis and anti-mildew activity of 5-(2-aroyl)aryloxymethyl-2-phenyl-1,3,4-oxadiazoles against downy mildew of pearl millet. Pest Management Science, 60 (11). pp. 1119-1124. ISSN 1526-498X

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Abstract

A manipulatively simple, rapid, high-yielding and environmentally benign method for the integration of a heterocyclic ring, 1,3,4-oxadiazole, at the benzophenone nucleus has been achieved through intramolecular cyclization of substituted aroylaryloxyacetohydrazides to substituted 5-(2-aroyl)aryloxy-methyl-2-phenyl- 1,3,4-oxadiazoles under solventless `dry' conditions using montmorillonite K10 clay and microwave irradiation. A comparison is made of the microwave-accelerated reaction with conventional heating conditions. Certain of the derivatives tested showed significant anti-mildew activity against Sclerospora graminicola (Sacc) Schroeter, the downy mildew pathogen of pearl millet. (C) 2004 Society of Chemical Industry.

Item Type:	Article
Uncontrolled Keywords:	microwave synthesis; benzophenone derivatives; antimildew activity; pearl millet
Subjects:	C Chemical Science > Chemistry
Divisions:	Department of > Chemistry
Depositing User:	Users 23 not found.
Date Deposited:	04 Sep 2019 09:38
Last Modified:	04 Sep 2019 09:38
URI:	http://eprints.uni-mysore.ac.in/id/eprint/6531

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