T3P®-DMSO mediated one pot cascade protocol for the synthesis of 4-thiazolidinones from alcohols

Sharath Kumar, K. S. and Swaroop, T. R. and Harsha, K. B. and Narasimhamurthy, K. H. and Rangappa, K. S. (2012) T3P®-DMSO mediated one pot cascade protocol for the synthesis of 4-thiazolidinones from alcohols. Tetrahedron Letters, 53 (42). 5619 - 5623. ISSN 0040-4039

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Official URL: https://doi.org/10.1016/j.tetlet.2012.08.020

Abstract

Propylphosphonic anhydride (T3P®)-DMSO mediated oxidation of alcohols to carbonyl compounds and their subsequent cyclization with aryl/hetero aryl amines and thioglycolic acid to afford 4-thiazolidinones has been reported. Synthesis of 4-thiazolidinones directly from alcohols has been carried out for the first time. Mild reaction conditions, wide functional group tolerance, ease of work-up, and good yields are the noteworthy features of this protocol.

Item Type: Article
Uncontrolled Keywords: Propylphosphonic anhydride (T3P®), Cascade, 4-Thiazolidinones, Thioglycolic acid (or mercaptoacetic acid)
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: C Swapna Library Assistant
Date Deposited: 17 Aug 2019 06:08
Last Modified: 17 Aug 2019 06:08
URI: http://eprints.uni-mysore.ac.in/id/eprint/6467

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