Synthesis, characterization, crystal and molecular structure analysis of N-(2,4-dimethylphenyl)-6-methyl-4-(3-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide

Naveen, S. and Adlakha, Priti and Dholakia, Chintan and Shah, Anamik and Sridhar, M. A. and Shashidhara Prasad, J. (2006) Synthesis, characterization, crystal and molecular structure analysis of N-(2,4-dimethylphenyl)-6-methyl-4-(3-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide. Structural Chemistry, 17 (6). pp. 569-575. ISSN 1572-9001

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A novel dihydropyrimidine (DHPM) derivative bearing a carbamoyl moiety was synthesized by an efficient three-component Biginelli reaction and was characterized spectroscopically and finally confirmed by X-ray diffraction studies. The title compound C20H20N4O4 crystallizes in the monoclinic space group P21/c with cell parameters a=12.8970(12) Å, b=13.6210(11) Å, c=11.8420(13) Å, β=115.860(3)°, Z=4 and V=1872.0(3) Å3. The conformation of the dihydropyrimidine ring is unusual; it is planar instead of the usual boat-like conformation. The 3-nitrophenyl ring is orthogonal to the 3,4-DHPM ring. The carbonyl group is in an anti-clinal conformation.

Item Type: Article
Subjects: D Physical Science > Physics
Divisions: Department of > Physics
Depositing User: LA manjunath user
Date Deposited: 12 Aug 2019 05:56
Last Modified: 11 Jul 2022 07:09

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