Synthesis and Crystal Structure of S-ethyl-2(tert-butoxycarbonylamino)-4-methyl-pentanethioate

Dinesh, B. and Manjunath, H. R. and Naveen, S. and Abiraj, K. and Ramesha Baba, A. and Channe Gowda, D. and Sridhar, M. A. and Shashidhara Prasad, J. (2010) Synthesis and Crystal Structure of S-ethyl-2(tert-butoxycarbonylamino)-4-methyl-pentanethioate. Molecular Crystals and Liquid Crystals, 517 (1). pp. 161-166. ISSN 1563-5287

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Abstract

S-ethyl-2(tert-butoxycarbonylamino)-4-methyl-pentanethioate (Boc-Leu-SEt) was synthesized by the mixed anhydride method IBCF/HOBt. The product obtained was characterized by 1H NMR, MS, and IR techniques, and finally confirmed by X-ray diffraction method. The compound crystallizes in the orthorhombic space group P212121 with cell parameters a=9.674(8)angstrom, b=10.659(7)angstrom, c=16.219(13)angstrom with Z=4. The structure exhibits both inter and intramolecular hydrogen bonds of the type N-H center dot center dot center dot O and C-H center dot center dot center dot O. The molecule possesses a chiral center at C9.

Item Type:	Article
Subjects:	C Chemical Science > Chemistry
Divisions:	Department of > Chemistry
Depositing User:	LA manjunath user
Date Deposited:	29 Jul 2019 05:44
Last Modified:	30 Jun 2022 08:57
URI:	http://eprints.uni-mysore.ac.in/id/eprint/6142

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