Synthesis of isoxazoles via 1,3-dipolar cycloaddition reactions and their antimicrobial activity

Kumar, K. and Govindaraju, M. and Vasanth Kumar, G. (2010) Synthesis of isoxazoles via 1,3-dipolar cycloaddition reactions and their antimicrobial activity. Indian Journal of Heterocyclic Chemistry, 20 (2). pp. 183-184. ISSN 0861-9808

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Abstract

The ethyl acetoacetate reacts with the nitrile imines generated in situ by the catalytic dehydrogenation of diphenyl hydrazones using chloramine-T (CAT) to afford regioselective cycloadducts in 80% yields respectively. The structures of these compounds have been characterized by FT-IR, (1)H NMR, (13)C NMR and mass spectroscopic techniques and elemental analysis. All the pyrazole derivatives have been tested for their antibacterial and antifungal activities.

Item Type: Article
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: LA manjunath user
Date Deposited: 28 Jul 2019 08:55
Last Modified: 11 Dec 2019 05:26
URI: http://eprints.uni-mysore.ac.in/id/eprint/5960

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