Swarup, H. A. and Chaithra, N. and Mantelingu, K. and Rangappa, K. S. (2018) Green synthetic approach for the construction of 3,5-disubstituted 1,2,4-oxadiazoles and ataluren analogues from dithioesters using water. ChemistrySelect, 3 (19). pp. 5390-5394. ISSN 2365-6549
Full text not available from this repository. (Request a copy)Abstract
An innovative green synthesis of 3,5‐disubstituted 1,2,4‐oxadiazoles from dithioesters using water as a solvent. This approach becomes more interesting because it undergoes nucleophilic substitution–dehydration–intramolecular cyclization in a single step to give 3,5‐disubstituted 1,2,4‐oxadiazoles in good to excellent yields under transition‐metal free conditions and allows wide functional group tolerance. This green protocol leads to synthesis of a drug lead molecule, Ataluren and their analogues.
| Item Type: | Article |
|---|---|
| Subjects: | C Chemical Science > Chemistry |
| Divisions: | Department of > Chemistry |
| Depositing User: | Manjula P Library Assistant |
| Date Deposited: | 26 Jul 2019 08:08 |
| Last Modified: | 26 Jul 2019 08:08 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/5925 |
Actions (login required)
 |
View Item |
