Raghavendra, K. R. and Girish, Y. R. and Ajay Kumar, K. and Shashikanth, S. (2015) Regioselective synthesis of n-formohydrazide and formyl pyrazole analogs as potent antimicrobial agents. Journal of Chemical and Pharmaceutical Research, 7 (6). pp. 361-366. ISSN 0975-7384
![[img]](http://eprints.uni-mysore.ac.in/style/images/fileicons/text.png) |
Text (Full Text)
CHE_2015_Raghavendra.pdf - Published Version Download (229kB) |
Abstract
A series of new (E)-N-(aryl)-N'-(1-(thiophen-2-yl)ethylidene)formohydrazides 2(a-g) and 1-(aryl)-3-(thiophen-2-yl)- 1H-pyrazole-4-carbaldehyde, 3(a-g) were prepared by the controlled Vilsmeier-Haack reaction. The reaction of (E)-1-aryl-2-(1-thiophen-2-yl)ethylidenehydrazines 1(a-g) with Vilsmeier-Haack reagent under different reaction conditions afforded the compounds 2(a-g) and 3(a-g) in good yield. The synthesized compounds were characterized by IR, 1H NMR, 13C NMR, Mass spectral, x-ray diffraction studies and elemental analysis. The compounds were screened for their antimicrobial susceptibility against different bacterium and fungi species
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Antibacterial and Antifungal and Formyl Pyrazoles and Hydrazines and Inhibition |
| Subjects: | C Chemical Science > Chemistry |
| Divisions: | Department of > Chemistry Yuvaraj college > Chemistry |
| Depositing User: | Users 19 not found. |
| Date Deposited: | 25 Jul 2019 06:00 |
| Last Modified: | 18 Jul 2022 07:25 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/5540 |
Actions (login required)
 |
View Item |
