Shwetha Hegde, G. and Dileep Kumar, A. and Ajay Kumar, K. (2015) Synthesis and antifungal activity of novel pyrimidin-2-one analogues. Journal of Chemical and Pharmaceutical Research, 7 (8). pp. 72-76. ISSN 0975-7384
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Abstract
A series of thiophene appended substituted pyrimidin-2-one analogues were synthesized by an accessible approach. The reaction of chalcones 1(a-e) and urea 2 in the presence potassium hydroxide in ethanol yielded 6-aryl-4- (thiophen-2-yl)-5,6-dihydropyrimidin-2(1H)-ones, 3(a-e) in good yields. The synthesized new compounds were characterized by 1H NMR, 13C NMR, Mass spectral studies and elemental analysis and were screened for their antifungal susceptibility against different fungi species
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Antifungal and Cyclocondensation and Inhibition and Pyrimidine and Urea |
| Subjects: | C Chemical Science > Chemistry |
| Divisions: | Yuvaraj college > Chemistry |
| Depositing User: | Users 19 not found. |
| Date Deposited: | 24 Jul 2019 09:37 |
| Last Modified: | 18 Jul 2022 07:26 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/5524 |
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