Raghavendra, K. R. and Ajay Kumar, K. and Renuka, N. and Dileep, C. S. and Lokanath, N. K. and Sridhar, M. A. and Shashikanth, S. (2015) Synthesis, characterization, antifungal activity and crystal structure of 1-(2-chlorophenyl)-3-(thiophen-2-yl)-1h-pyrazole-4-carboxaldehyde. Journal of Chemical and Pharmaceutical Research, 7 (12). pp. 842-848. ISSN 0975-7384
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Abstract
1-(2-Chlorophenyl)-3-(thiophen-2-yl)-1H-pyrazole-4-carboxaldehyde (3) was synthesized by the reaction of (Z)-1- (2-chlorophenyl)-2-(1-(thiophen-2-yl)ethylidene)hydrazine (2) and Vilsmeier-Haack (DMF, POCl3) reaction. The synthesised compound was characterized by spectroscopy and elemental analysis. The crystal structure was determined from single crystal X-ray diffraction data. It crystallizes in the triclinic crystal system with the space group P-1 and with unit cell parameters a= a = 7.2562(12) à , b= 8.6896(11) à , c =11.4407(16) à ; a = 109.168(7)º, b= 105.648(7)º, . = 94.4099(8)º and Z = 2. The crystal structure is stabilized by intramolecular C--- H...O hydrogen bonds
Item Type: | Article |
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Uncontrolled Keywords: | Antifungal and Diffusion and Packing and Spectral Studies and X-Ray Diffraction |
Subjects: | C Chemical Science > Chemistry |
Divisions: | Yuvaraj college > Chemistry |
Depositing User: | Users 19 not found. |
Date Deposited: | 24 Jul 2019 05:56 |
Last Modified: | 18 Jul 2022 07:27 |
URI: | http://eprints.uni-mysore.ac.in/id/eprint/5502 |
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