Design and synthesis of novel pyrazolines as potent antimicrobial and antioxidant agents

Vasanth Kumar, G. and Bi Bi Ahmadi Khatoon and Ajay, K. (2015) Design and synthesis of novel pyrazolines as potent antimicrobial and antioxidant agents. Journal of Chemical and Pharmaceutical Research, 7 (4). pp. 854-859. ISSN 0975-7384

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Abstract

The nitrile imines generated by the oxidative dehydrogenation of aldehyde phenylhydrazones with chloramine-T in ethyl alcohol undergo 1,3-dipolar cycloaddition with benzalacetone in situ to afford 1-(3-aryl-1,4-diphenyl-4,5- dihydro-1H-pyrazol-5-yl)ethanones in good yield. The structure proofs of the synthesized new cycloadducts were provided by IR, 1H NMR, 13C NMR, Mass spectral studies and elemental analysis. The new compounds were evaluated in vitro for their antimicrobial and antioxidant activities

Item Type: Article
Uncontrolled Keywords: Antibacterial and Antifungal and Antioxidant and Chloramine-T and Dipolar and Nitrile Imines
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: Shrirekha N
Date Deposited: 24 Jul 2019 05:30
Last Modified: 18 Sep 2019 06:01
URI: http://eprints.uni-mysore.ac.in/id/eprint/5491

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