Vijaychand, S. P. and Pavithra, G. and Raghavendra, K. R. and Ajay, K. (2015) An efficient route to synthesis of pyrazoline carboxamides bearing thiophene moiety as antimicrobial agents. Der Pharma Chemica, 7 (4). pp. 85-89. ISSN 0975-413X
Full text not available from this repository. (Request a copy)Abstract
A series of new pyrazoline carbothioamides bearing thiophene moiety were synthesized by simple one pot procedure. The cyclocondensation reaction of chalcones 1a-g and semicarbazine 2 in the presence potassium hydroxide in ethanol yielded 5-(4-aryl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole-1-carboxamides 3a-g in excellent yield. The synthesized new products were characterized by 1H NMR, 13C NMR, Mass spectral studies and elemental analysis. The compounds were tested for their antimicrobial susceptibility against different bacterium and fungi species.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Antibacterial and Antifungal and Carboxamide and Cyclocondensation and Inhibition |
| Subjects: | C Chemical Science > Chemistry |
| Divisions: | Yuvaraj college > Chemistry |
| Depositing User: | Users 19 not found. |
| Date Deposited: | 23 Jul 2019 07:25 |
| Last Modified: | 16 Jul 2022 07:05 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/5473 |
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