One-pot synthesis of aryl oxime analogues from methyl arenes using NBS and hydroxyl amine hydrochloride

Chandrappa, S. and Umashankara, M. and Vinaya, K. and Ananda Kumar, C. S. and Rangappa, K. S. (2012) One-pot synthesis of aryl oxime analogues from methyl arenes using NBS and hydroxyl amine hydrochloride. Tetrahedron Letters, 53 (21). 2632 - 2635. ISSN 0040-4039

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Official URL: https://doi.org/10.1016/j.tetlet.2012.03.052

Abstract

The one-pot synthesis of aryl oximes is reported by the reaction of methyl arenes with NBS using hydroxyl amine hydrochloride. The direct conversion of methyl group into oxime group has been achieved under mild reaction conditions in the presence of sensitive functional groups including chloro, bromo, cyano, hydroxy, fluoro, dioxaborolane, esters, and trifluoro methyl substituents with excellent yields. The simple experimental procedure and easy purification make this protocol advantageous.

Item Type: Article
Uncontrolled Keywords: Aryl oximes, -Bromo succinamide (NBS), Methyl arenes, Hydroxyl amine hydrochloride, Benzoyl peroxide
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: C Swapna Library Assistant
Date Deposited: 20 Jul 2019 10:30
Last Modified: 20 Jul 2019 10:30
URI: http://eprints.uni-mysore.ac.in/id/eprint/5417

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