Fuller’s earth catalyzed rapid synthesis of bis (indolyl) methanes under solvent free condition

Kapuriya, Naval and Kakadiya, Rajesh and Savant,, Mahesh M and Pansuriya, Akshay M and Bhuva, Chirag V and Patel, Anil S and Pipaliya, Piyush V and Audichya, Vipul B and Sarala, Gangadharaiah and Anandalwar, Sridhar M. and Prasad, Javaregowda S. and Shah, Anamik and Naliapara, Yogesh T (2012) Fuller’s earth catalyzed rapid synthesis of bis (indolyl) methanes under solvent free condition. Indian Journal Of Chemistry Section B Organic Chemistry Including Medicinal Chemistry, 51 (7). pp. 1032-1038. ISSN 0975-0983

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Abstract

A rapid and highly efficient synthesis of various bis(indolyl)methanes with high yield by the reaction of indoles 1a-c and arylaldehydes 2a'-m' in presence of fuller’s earth is demonstrated. This simple and versatile protocol is found to be an efficient catalyst for the electrophilic addition reaction of indole and works well under solvent free condition as well as in aqueous medium. The structure of newly synthesized compound 3m has been confirmed by single crystal X-ray crystallography.

Item Type: Article
Uncontrolled Keywords: Fuller’s earth;Electrophilic addition;Bis(indolyl)¬methanes;Water mediated;Solvent free condition
Subjects: D Physical Science > Physics
Divisions: Department of > Physics
Depositing User: MUL SWAPNA user
Date Deposited: 19 Jul 2019 09:07
Last Modified: 19 Jul 2019 09:07
URI: http://eprints.uni-mysore.ac.in/id/eprint/5364

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