Study on the Serum Titer of Anti-Hbs Antibody of the Vaccinated Staffs of A Hospital in Three Consecutive Years

Mohsenzade, Mehdi and Pirouzi, Aliyar and Jafari, Mohammad and Azadi, Mehdi and Jahromi, Sareh Raeiszadeh and Afkar, Rouhi (2013) Study on the Serum Titer of Anti-Hbs Antibody of the Vaccinated Staffs of A Hospital in Three Consecutive Years. Zahedan Journal of Research in Medical Sciences, 15 (12). pp. 23-27.

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Abstract

Hepatitis B virus is one of the main factors causing acute and chronic hepatitis and hepatocellular carcinoma. Among others, healthcare workers are at the highest risk for exposure to hepatitis B virus. Vaccination against hepatitis B virus is one of the protective strategies but anti-HBs titer will be reduced in the sera of vaccinated people after some time. The aim of this study was to determine the titer of anti-HBs in the sera of vaccinated medical staffs in three consecutive years since administration of the last dose of hepatitis B vaccine.Materials and Methods : This study was carried out on 90 Omidvar Hospital (Lar, Iran) medical staffs that had passed 3-4 months since the administration of the last dose of hepatitis B vaccine. All sera samples were tested for anti-HBs in an ELISA method. Finally, statistical analysis was performed using SPSS-16 software.Results : This study was conducted in duration of 3 consecutive years on 90 medical staffs including 14.44% lab technicians, 10% obstetricians, 43.35% nurses, 6.665% specialists, 5.55% general practitioners and 20% maid staffs. While HBs Ab titer was measured as 87.7% (>100 mIU/ml) in the first year elapsed since the last dose of hepatitis B vaccination, it had been decreased to 55.4% after 3 years.Conclusion : The results showed that re-vaccination of the medical staffs is quite necessary as anti-HBs titer had been decreased after 3 years and the desired immune response was seen only in 55.4% of the medical staffs.

Item Type: Article
Subjects: Q Science > QL Zoology
Divisions: Faculty of Science > Zoology
Depositing User: lpa manjula editor
Date Deposited: 25 May 2019 07:08
Last Modified: 25 May 2019 07:08
URI: http://eprints.uni-mysore.ac.in/id/eprint/527

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