2-Butyl-5-chloro-3H-imidazole-4-carbaldehyde as a new synthon for the synthesis of fused ring heterocycles via intramolecular 1,3-dipolar cycloaddition reactions

Gaonkar, Santosh L. and Rai, K. M. Lokanatha (2010) 2-Butyl-5-chloro-3H-imidazole-4-carbaldehyde as a new synthon for the synthesis of fused ring heterocycles via intramolecular 1,3-dipolar cycloaddition reactions. Journal of Heterocyclic Chemistry, 47 (3). pp. 543-546. ISSN 1943-5193

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Official URL: https://onlinelibrary.wiley.com/doi/abs/10.1002/jh...

Abstract

Abstract The title compound 2-butyl-5-chloro-3H-imidazole-4-carbaldehyde was transformed into tricyclic heterocycles by substituting the chlorine atom by an unsaturated thiolate or alkoxide and then converting aldehyde function into 1,3-dipole. Chloramine-T was used as an efficient reagent for the generation of 1,3-dipoles, which resulted the formation of fused ring heterocycles via intramolecular 1,3-dipolar cycloaddition reaction. The method is very useful for the construction of many biologically active fused heterocycles. J. Heterocyclic Chem., (2010).

Item Type: Article
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: LA manjunath user
Date Deposited: 12 Jul 2019 10:25
Last Modified: 19 Jan 2023 06:02
URI: http://eprints.uni-mysore.ac.in/id/eprint/5152

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