Wang, Meng and Rakesh, K. P. and Leng, Jing and Fang, Wan-Yin and Ravindar, L. and Channe Gowda, D. and Qin, Hua-Li (2018) Amino acids/peptides conjugated heterocycles: A tool for the recent development of novel therapeutic agents. Bioorganic Chemistry, 76. 113 - 129. ISSN 1090-2120
Full text not available from this repository. (Request a copy)Abstract
Amino acids/peptide conjugated heterocycles represent an important class of therapeutical agents. Biologically active heterocycles are conjugated with amino acids or peptides to increase the drug resistance. Furthermore, the amino acid/peptide based drugs have low toxicity, ample bioavailability and permeability, modest potency and good metabolic and pharmacokinetic properties. Synthetic amino acid/peptides based heterocyclic conjugates constitute a promising choice for the development of new, less toxic and safer conventional pharmaceutical drugs in the near future. In this review, we discuss and highlight the recent findings of the structural features that encourage biological applications of amino acid/peptides based conjugates.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Amino acids, Peptides, Conjugation, Heterocycles, Biological activities, SAR |
| Subjects: | C Chemical Science > Chemistry |
| Divisions: | Department of > Chemistry |
| Depositing User: | Manjula P Library Assistant |
| Date Deposited: | 12 Jul 2019 05:30 |
| Last Modified: | 12 Jul 2019 05:30 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/5105 |
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