Neolithic phylogenetic continuity inferred from complete mitochondrial DNA sequences in a tribal population of Southern India

Sylvester, Charles and Krishna, M. S. and Rao, Jaya Sankar and Chandrasekar, Adimoolam (2018) Neolithic phylogenetic continuity inferred from complete mitochondrial DNA sequences in a tribal population of Southern India. Genetica, 146 (4-5). pp. 383-389. ISSN 1573-6857

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Abstract

The subsequent human migrations that dispersed out of Africa, both prehistoric and historic and colonization of India by modern humans is unanimous, and phylogeny of major mitochondrial DNA haplogroups have played a key role in assessing the genetic origin of people of India. To address more such events, complete mitogenomes of 113 Melakudiya tribe of Southern India were sequenced and 46 individuals showed the presence of west Eurasian autochthonous haplogroups HV14 and U7. Phylogenetic analysis revealed two novel subclades HV14a1b and HV14a1b1 and sequences representing haplogroup U7 were included under previously described subclade U7a3a1a2* specific to India. Moreover, the present analysis on complete mtDNA reveals addition information of the spread and distribution of west Eurasian haplogroups in southern India, in tracing an unexplored genetic link between Melakudiya tribe with the people of Iranian Plateau, South Caucasus, and Central Asia. Coalescence ages of HV14 and U7a3a1a2* trees in the present study dates ~ 16.1 ± 4.3 and ~ 13.4 ± 5.6 kya respectively.

Item Type:	Article
Subjects:	B Life Science > Zoology
Divisions:	Department of > Zoology
Depositing User:	Manjula P Library Assistant
Date Deposited:	06 Jul 2019 06:33
Last Modified:	06 Jul 2019 06:33
URI:	http://eprints.uni-mysore.ac.in/id/eprint/4821

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