A catalyst-free green protocol for the synthesis of pyranopyrazoles using room temperature ionic liquid choline chloride-urea

Swaroop, T. R. and Sharath Kumar, K. S. and Palanivelu, M. and Chaitanya, S. and Rangappa, K. S. (2014) A catalyst-free green protocol for the synthesis of pyranopyrazoles using room temperature ionic liquid choline chloride-urea. Journal of Heterocyclic Chemistry, 51 (6). pp. 1866-1870.

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Official URL: https://doi.org/10.1002/jhet.1864

Abstract

An efficient and rapid four component reaction of aldehydes, malanonitrile, β-ketoesters and hydrazine hydrate (or phenyl hydrazine) in environmentally benign room temperature ionic liquid choline chloride-urea has been developed for the synthesis of substituted 4H-pyrano2,3-cpyrazoles.

Item Type: Article
Uncontrolled Keywords: 4, Article, drug synthesis, unclassified drug, drug structure, pyrazole derivative, X ray crystallography, room temperature, urea, chemical reaction, Michael addition, catalyst, crystallization, cyclization, hydrazine, choline, ionic liquid, ester, aldehyde, 5 trimethoxyphenyl) 2, 3 c] 2, 3 c]pyrazole 5 carbonitrile, 4 dihydropyrano2, 4 dimethoxyphenyl) 3 methyl 2, 4 diphenyl 1, 4 diphenyl 2, 6 amino 3, 6 amino 3 isopropyl 1 phenyl 4 (pyridin 3 yl) 1, 6 amino 3 isopropyl 4 (3, 6 amino 3 isopropyl 4 (4 nitrophenyl) 2, 6 amino 3 isopropyl 4 (pyridin 3 yl) 2, 6 amino 3 methyl 1, 6 amino 3 methyl 4 (1 methyl 1h indol 3 yl) 2, 6 amino 3 methyl 4 (3, 6 amino 3 methyl 4 (pyridin 3 yl) 2, 6 amino 3 methyl 4 phenyl 2, 6 amino 4 (3, 6 amino 4 (4 (dimethylamino)phenyl) 3 methyl 2, 6 amino 4 (4 ethoxyphenyl) 3 isopropyl 2, 6 amino 4 (4 methoxyphenyl) 3 methyl 2, 6 amino 4 (furan 2 yl) 3 methyl 2, 6amino 3 isopropyl 4 (4 nitrophenyl) 1 phenyl 1, beta ketoester, pyrazolone, tautomerization
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: Arshiya Kousar Library Assistant
Date Deposited: 14 Jul 2019 10:07
Last Modified: 14 Jul 2019 10:07
URI: http://eprints.uni-mysore.ac.in/id/eprint/4431

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