One-pot tandem synthesis of tetrasubstituted pyrazoles via 1,3-dipolar cycloaddition between aryl hydrazones and ethyl but-2-ynoate

Ningaiah, S. and Doddaramappa, S. D. and Chandra and Madegowda, M. and Keshavamurthy, S. and Bhadraiah, U. K. (2014) One-pot tandem synthesis of tetrasubstituted pyrazoles via 1,3-dipolar cycloaddition between aryl hydrazones and ethyl but-2-ynoate. Synthetic Communications, 44 (15). pp. 2222-2231.

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Abstract

1,3,4,5-Tetrasubstituted pyrazoles are rapidly and regioselectively synthesized in a one-pot, three-step sequence consisting of condensation, nitrilimine generation, and cycloaddition using mercuric acetate. Newly synthesized compounds were characterized by spectral studies. Regiochemistry of compounds 6a and 8a was determined as 1,4- and 1,5-regioisomers respectively by X-ray crystallography.

Item Type:	Article
Uncontrolled Keywords:	carbon nuclear magnetic resonance, proton nuclear magnetic resonance, polymerization, stereochemistry, pyrazole derivative, hydrazone derivative, X ray crystallography, article, cycloaddition, one pot synthesis, nitrile, reaction analysis, polycyclic aromatic hydrocarbon derivative, alkanoic acid, alkyl group, dipole, imine, mercury derivative
Subjects:	C Chemical Science > Chemistry D Physical Science > Physics
Divisions:	Department of > Chemistry Department of > Physics Yuvaraj college > Chemistry
Depositing User:	Arshiya Kousar Library Assistant
Date Deposited:	03 Sep 2019 10:18
Last Modified:	03 Sep 2019 10:18
URI:	http://eprints.uni-mysore.ac.in/id/eprint/3944

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