Synthesis, characterization and biological evaluation of cyclic peptides: Viscumamide, yunnanin A and evolidine

Poojary, B. and Belagali, S. L. (2005) Synthesis, characterization and biological evaluation of cyclic peptides: Viscumamide, yunnanin A and evolidine. ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 60 (12). pp. 1313-1320.

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Abstract

Three biologically active cyclic peptides, viscumamide, yunnanin A and evolidine were synthesized and the structures were established on the basis of analytical, IR, NMR and mass spectral data. These newly synthesized cyclic peptides were evaluated for antimicrobial and pharmacological activities. Evolidine showed better growth inhibition against bacterial strains than yunnanin A and viscumamide. The anti-inflammatory activity of viscumamide is moderate and the remaining two cyclic peptides are found to be less active. But, all the three cyclic peptides showed weak anthelmintic activity.

Item Type: Article
Uncontrolled Keywords: cyclic peptides; viscumamide; yunnanin A; evolidine; antimicrobial activity
Subjects: Physical Sciences > Environmental Science
Divisions: PG Campuses > Manasagangotri, Mysore > Environmental Science
Depositing User: Users 9 not found.
Date Deposited: 08 Apr 2013 11:32
Last Modified: 25 Jul 2013 05:30
URI: http://eprints.uni-mysore.ac.in/id/eprint/3472

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