Girish, Y. R. and Sharath Kumar, K. S. and Muddegowda, U. and Lokanath, N. K. and Rangappa, K. S. and Shashikanth, S. (2014) ZrO2-supported Cu(II)-β-cyclodextrin complex: Construction of 2,4,5-trisubstituted-1,2,3-triazoles via azide - Chalcone oxidative cycloaddition and post-triazole alkylation. RSC Advances, 4 (99). pp. 55800-55806. ISSN 2046-2069
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Abstract
An efficient one-pot three-component stepwise approach for the synthesis of N-2-substituted-1,2,3-triazoles from chalcones, sodium azide and esters has been developed using a recoverable and reusable ZrO2 nanoparticle-supported Cu(II)-β-cyclodextrin complex as a catalyst. N-2 alkylation of triazoles using different aryl-alkyl esters without any additives has been achieved for the first time. The one-pot operation, atom-economical nature, regioselectivity and good yields are the noteworthy features of this protocol. The reusability of the prepared nanocatalyst was successfully examined four times without any appreciable loss in catalytic activity.
Item Type: | Article |
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Uncontrolled Keywords: | Chalcones, Cyclodextrin complexes, Supported Cu |
Subjects: | C Chemical Science > Chemistry D Physical Science > Physics |
Divisions: | Department of > Chemistry Department of > Physics |
Depositing User: | Arshiya Kousar Library Assistant |
Date Deposited: | 19 Jun 2019 11:22 |
Last Modified: | 19 Jun 2019 11:22 |
URI: | http://eprints.uni-mysore.ac.in/id/eprint/3329 |
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