A facile and green strategy for the synthesis of Au, Ag and Au–Ag alloy nanoparticles using aerial parts of R. hypocrateriformis extract and their biological evaluation

Godipurge, S. S. and Yallappa, S. and Biradar, Naveen J. and Biradar, J. S. and Dhananjaya, B. L. and Hegde, Gajanan and Jagadish, K. and Hegde, Gurumurthy (2016) A facile and green strategy for the synthesis of Au, Ag and Au–Ag alloy nanoparticles using aerial parts of R. hypocrateriformis extract and their biological evaluation. Enzyme and Microbial Technology, 95. 174 - 184.

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Abstract

A facile and green strategy is reported here to synthesize gold (Au), silver (Ag) and gold–silver (Au–Ag) alloy nanoparticles (NPs) through bio-reduction reactions of aqueous corresponding metal precursors mediated by extracts of aerial parts of R. hypocrateriformis, which act as both reducing and stabilizing agents, under microwave irradiation. UV–vis spectrophotometer, XRD, FT-IR, FESEM/TEM, TGA and EDAX analysis were used to characterize the obtained NPs. The formation of NPs is evident from their surface plasmon resonance peak observed at λmax=∼550, 450 and 500nm for Au, Ag and Au–Ag alloy NPs respectively. XRD pattern revealed that fcc structure, while FT–IR spectra signify the presence of phytochemicals adsorbed on NPs. Such a biofunctionalized NPs were characterized by their weight loss, 30 due to thermal degradation of plant phytochemicals observed in TG analysis. The spherical shape of Au, Ag and Au–Ag alloy NPs (∼10–50nm) is observed by FE-SEM/TEM images. EDAX analysis confirms the expected elemental composition. Moreover, these NPs showed enhanced antimicrobial, antioxidant, and anticancer activities, though it is more pronounced for Au–Ag alloy NPs, which is due to the combining effect of phytochemicals, Au and Ag metals. Thus, the biosynthesized NPs could be applied as effective growth inhibitors for various biomedical applications.

Item Type: Article
Additional Information: Biosynthetic nanoparticles for biotechnological and biomedical applications
Uncontrolled Keywords: Gold-silver alloys, , Antimicrobial activity, Antioxidant activity, Anticancer activity
Subjects: D Physical Science > Material Science
Divisions: Department of > Material Science
Depositing User: Manjula P Library Assistant
Date Deposited: 18 Jun 2019 07:12
Last Modified: 28 Dec 2020 06:00
URI: http://eprints.uni-mysore.ac.in/id/eprint/3308

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