In Vitro antioxidant, antibacterial and phytochemical screening of Cochlospermum religiosum (L.) Alston - A potent medicinal plant

Pooja, Ponnamma and Manasa, G. and Sudarshana, M. S. and Murali, M. and Mahendra, C. (2017) In Vitro antioxidant, antibacterial and phytochemical screening of Cochlospermum religiosum (L.) Alston - A potent medicinal plant. Tropical Plant Research, 4 (1). pp. 13-19. ISSN 2349-1183

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Official URL: https://doi.org/10.22271/tpr.2017.v4.i1.003

Abstract

The work is undertaken to evaluate the preliminary phytochemicals, antibacterial and antioxidants activity of Cochlospermum religiosum leaf extracts with three solvents via chloroform, ethyl acetate and methanol based on polarity index. The antibacterial activity was assessed against five bacterial pathogens like Escherichia coli, Bacillus subtilis, Bacillus cereus, Staphylococcus aureus and Pseudomonas aeruginosa by well diffusion assay. Among the tested pathogens, the maximum zone of inhibition was observed against E. coli (26 mm) followed by P. aeruginosa (23 mm) in ethyl acetate extracts compare to other solvent extracts. Phytochemical analysis also revealed the presence of various pharmaceutically active secondary metabolites like alkaloids, phenolic, flavonoids, saponins, carbohydrates, proteins, glycosides, sterols, etc. Antioxidant activity was determined by DPPH scavenging, total phenolic and phospho-molybdenum method. In DPPH assay, ethyl acetate extract was found to be the most effective. Similarly, total phenols and phospho-molybdenum assay the methanol extracts was found to contained good sources of antioxidants. The outcomes of the present study specified the plant possess various potentially active secondary metabolites which help for the developing pharmaceuticals, especially antioxidant and antimicrobial drugs.

Item Type: Article
Subjects: B Life Science > Botany
Divisions: Department of > Botany
Depositing User: MUL SWAPNA user
Date Deposited: 17 Jun 2019 06:00
Last Modified: 17 Jun 2019 06:00
URI: http://eprints.uni-mysore.ac.in/id/eprint/3223

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