Chandrashekar, M. and Dileep Kumar, A. and Pavithra, G. and Renuka, N. and Ajay Kumar, K. (2016) Synthesis of novel bioactive pyrazole carbothioamides and their antifungal activity studies. Der Pharma Chemica, 8 (4). pp. 118-121. ISSN 0975-413X
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Abstract
A series of new pyrazoline carbothioamides bearing furan moiety were synthesized by simple one pot procedure. The method involves base catalyzed cyclocondensation reaction of chalcones 1a-e and thiosemicarbazide 2 in ethanol under optimum temperature. The reaction yielded the title compounds 5-aryl-3-(furan-2-yl)-4,5-dihydro-1H-pyrazole-1-carbothioamides 3a-e in excellent yields. The synthesized new compounds were characterized by spectral studies and elemental analysis, and were evaluated in vitro for their antifungal susceptibility.
| Item Type: | Article |
|---|---|
| Subjects: | C Chemical Science > Chemistry |
| Divisions: | Yuvaraj college > Chemistry |
| Depositing User: | Manjula P Library Assistant |
| Date Deposited: | 14 Jun 2019 07:38 |
| Last Modified: | 18 Jul 2022 07:00 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/3086 |
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