Global spectrum of copy number variations reveals genome organizational plasticity and proposes new migration routes

Veerappa, A. M. and Vishweswaraiah, S. and Lingaiah, K. and Murthy, M. and Suresh, R. V. and Manjegowda, D. S. and Ramachandra, N. B. (2015) Global spectrum of copy number variations reveals genome organizational plasticity and proposes new migration routes. PLOS ONE, 10 (4). ISSN 1932-6203

[img] Text (Full Text)
ZOO_2015_Veerappa.PDF - Published Version

Download (5MB)
Official URL: https://doi.org/10.1371/journal.pone.0121846

Abstract

Global spectrum of CNVs is required to catalog variations to provide a high-resolution on the dynamics of genome-organization and human migration. In this study, we performed genome-wide genotyping using high-resolution arrays and identified 44,109 CNVs from 1,715 genomes across 12 populations. The study unraveled the force of independent evolutionary dynamics on genome-organizational plasticity across populations. We demonstrated the use of CNV tool to study human migration and identified a second major settlement establishing new migration routes in addition to existing ones.

Item Type: Article
Subjects: B Life Science > Sericulture
Divisions: Department of > Zoology
Depositing User: Shrirekha N
Date Deposited: 11 Jun 2019 09:20
Last Modified: 11 Jun 2019 09:20
URI: http://eprints.uni-mysore.ac.in/id/eprint/2742

Actions (login required)

View Item View Item