Simple and selective spectrophotometric assay of diethylcarbamazine citrate using 2,3-dichloro-5,6-dicyano-p-benzoquinone and 2,4-dinitro phenol

Swamy, N. and Basavaiah, K. (2015) Simple and selective spectrophotometric assay of diethylcarbamazine citrate using 2,3-dichloro-5,6-dicyano-p-benzoquinone and 2,4-dinitro phenol. QUIMICA NOVA, 38 (5). pp. 715-722. ISSN 1678-7064

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Official URL: https://doi.org/10.5935/0100-4042.20150061

Abstract

Two simple, rapid and inexpensive spectrophotometric methods are described for the determination of diethylcarbamazine citrate (DEC) in bulk drug and formulations. The methods are based on the charge-transfer (CT) complexation reaction involving DEC as the n- donor and 2,3-dichloro-5,6-dicyano-p-benzoquinone DDQ] (method A) and 2,4-dinitro phenol DNP] (method B) as pi-acceptors in chloroform. The absorbance of CT complexes was measured at 480 nm for method A, and 420 nm for method B. Under optimum conditions, Beer's law was obeyed over the concentration ranges 4-90 and 4-100 mu g mL(-1) for methods A and B, respectively.

Item Type: Article
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: Shrirekha N
Date Deposited: 07 Jun 2019 10:22
Last Modified: 07 Jun 2019 10:22
URI: http://eprints.uni-mysore.ac.in/id/eprint/2729

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