Synthesis and antimicrobial activity of 2-Methyl-5-nitroaniline derivatives: A structure-activity relationship study

Lingappa, M. and Mohana, K. N. and Devaraju, R. and Sreedharamurthy, S. (2011) Synthesis and antimicrobial activity of 2-Methyl-5-nitroaniline derivatives: A structure-activity relationship study. CHINESE JOURNAL OF CHEMISTRY, 29 (1). pp. 102-108.

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Abstract

A series of 2-methyl-5-nitroaniline derivatives, 5a-5k and 6a-6f, were synthesized in order to determine their in vitro antimicrobial activity. The chemical structures of the synthesized compounds were confirmed by elemental analyses, UV-visible, FT-IR, H-1 NMR and C-13 NMR spectral studies. The structure-activity relationships of the synthesized compounds were also discussed. Among the synthesized compounds, 5f, 5d, 6b and 6e showed good antimicrobial activity compared to standard drugs.

Item Type: Article
Uncontrolled Keywords: 2-methyl-5-nitroaniline; aldehydes; ketones; antimicrobials
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: Users 23 not found.
Date Deposited: 13 Jun 2019 12:52
Last Modified: 11 Dec 2019 09:22
URI: http://eprints.uni-mysore.ac.in/id/eprint/2609

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