Synthesis of new polysubstituted (pyrazoles, pyrimidines and quinolines) five and six-membered heterocycles: reaction of alpha,alpha-dioxoketene dithioacetals with nucleophiles

Ebraheem, M. A. and Rai, K. M. Lokanatha and Kudva N, N. U. and Bahjat, A. S. (2010) Synthesis of new polysubstituted (pyrazoles, pyrimidines and quinolines) five and six-membered heterocycles: reaction of alpha,alpha-dioxoketene dithioacetals with nucleophiles. TETRAHEDRON LETTERS, 51 (27). pp. 3486-3492.

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Official URL: http://dx.doi.org/10.1016/j.tetlet.2010.04.003

Abstract

A novel synthesis of polysubstituted pyrazoles 3a-d, pyrimidines 4a-f and quinolines 5a-c via the reaction of alpha,alpha-oxoketene dithioacetals 2a-c with hydrazine hydrate, malonohydrazide, urea, thiourea and aniline is reported and the synthetic potential of the method is demonstrated. The structure of the new compounds was established upon their elemental analysis, IR, (1)H NMR and (13)C NMR. (C) 2010 Elsevier Ltd. All rights reserved.

Item Type: Article
Uncontrolled Keywords: alpha,alpha-Oxoketene dithioacetals; Polysubstituted pyrazole; Pyrimidines and quinolines
Subjects: Physical Sciences > Chemistry
Divisions: PG Campuses > Manasagangotri, Mysore > Chemistry
Depositing User: Users 7 not found.
Date Deposited: 27 Mar 2013 07:10
Last Modified: 22 Aug 2013 06:17
URI: http://eprints.uni-mysore.ac.in/id/eprint/2591

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