Synthesis of isoxazolines: small molecules of potent antimicrobial activity

Manjula, N. and Lokeshwari, D. M. and Dileep Kumar, A. and Renuka, N. and Ajay Kumar, K. (2017) Synthesis of isoxazolines: small molecules of potent antimicrobial activity. Der Pharma Chemica, 9 (13). pp. 7-10. ISSN 0975-413X

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A simple procedure for the synthesis of isoxazole derivatives was developed. Cyclocondensation reaction of chalcones with hydroxylamine hydrochloride catalyzed by an acid produced isoxazoles in good yields. The synthesized new compounds were characterized by spectral studies and elemental analysis; before being were screened in vitro for their antimicrobial susceptibilities against different bacteria and fungi species.

Item Type: Article
Subjects: Physical Sciences > Chemistry
Divisions: Constituent Colleges > Yuvaraja's College Mysore > Chemistry
Depositing User: Praveen Kumari B.L
Date Deposited: 08 Dec 2017 05:31
Last Modified: 08 Dec 2017 05:31

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