Efficient synthesis of novel diorganyl selenides via cleavage of se–se bond of diselenides by RUCL3/ZN and screened for their biological efficacy

Ashok, B. and Kumar Naik, K. H. and Avinash, P. and Nagaraja Naik , (2016) Efficient synthesis of novel diorganyl selenides via cleavage of se–se bond of diselenides by RUCL3/ZN and screened for their biological efficacy. World Journal of Pharmaceutical Research, 5 (2). pp. 608-618. ISSN 2277– 7105

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Abstract

The RuCl3-catalysed cross-coupling reaction of novel diorganyl diselenides with benzyl halides using Zinc as an additive. This cross-coupling reaction was performed with amide conjugated diaryl diselenides with benzyl halides bearing electron-withdrawing and electron-donating groups, affording corresponding diaryl selenides in good yield and further characterized by using Mass, 1H NMR, 13C NMR, 77Se NMR and elemental analysis. The title compounds were evaluated for their in vitro Antioxidant and Antibacterial activity.

Item Type: Article
Subjects: Physical Sciences > Chemistry
Divisions: PG Campuses > Manasagangotri, Mysore > Chemistry
Depositing User: Praveen Kumari B.L
Date Deposited: 21 Sep 2017 10:06
Last Modified: 21 Sep 2017 10:06
URI: http://eprints.uni-mysore.ac.in/id/eprint/19980

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