Screening for bioactives from Indian medicinal herbs–a simplistic approach for antioxidant metabolites

Beulah, K. C. and Aishwarya T. Devi, and Waseem, K. and Hedgekatte, R. and Nagendra Prasad, M. N. and Dhananjaya, B. L. and Farhan Zameer, (2015) Screening for bioactives from Indian medicinal herbs–a simplistic approach for antioxidant metabolites. International Journal of Pharmacy and Pharmaceutical Sciences, 7 (1). pp. 195-198. ISSN 0975-1491

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Herbal extracts obtained from 20 Indian medicinal plants were evaluated for their cytoprotectivity on erythrocytes and antioxidant properties. Total phenol content and anti-rhizopus activity were also determined. Results indicated that, out of 20 extracts evaluated, radical scavenging capacity and anti-rhizopus activity were observed in aqueous extract of Ocimum tenuiflorum, Leucas aspera, Terminalia arjuna, Glycyrrhiza glabra and Nyctanthes arbortristis in a dose dependent manner. The total phenolic content was observed to be 1289, 3837, 372, 2831 and 1892 μg GAE/g for O. tenuiflorum, L. aspera, T. arjuna, G. glabra and N. arbortristis respectively. The antioxidant activity correlates with the phenolic content of the extracts. At 1 mg/ml the above extracts showed 98% protection on erythrocyte cell oxidation. These results demonstrate that the cytoprotectivity and antioxidant potency of these extracts could be the basis for their alleged health promoting potential. These herbs could serve as new sources of natural antioxidants or nutraceuticals with potential applications in reducing oxidative stress conditions.

Item Type: Article
Subjects: Physical Sciences > Chemistry
Divisions: PG Campuses > Manasagangotri, Mysore > Chemistry
Depositing User: Praveen Kumari B.L
Date Deposited: 14 Dec 2016 10:28
Last Modified: 14 Dec 2016 10:28

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