An insight into the understanding of 5-HTR2A variants leading to schizophrenia

Kusuma, L. and Ramachandra, N. B. (2014) An insight into the understanding of 5-HTR2A variants leading to schizophrenia. The Indian Journal of Medical Research, 140 (6). pp. 713-715. ISSN 0971-5916; 0975-9174

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Official URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC436534...

Abstract

Schizophrenia is one of the most important mental disorders which is characterized by a deep disruption of the thinking process and of emotional response1. It is a disabling group of brain disorders that has symptoms of hallucinations, delusions, disorganized communication, poor planning, reduced motivation and blunted affect2. The incidence of schizophrenia is relatively low (median value 15.2 per 100,000/year) and is one of the major contributors to the global burden of disease2,3. In India, the prevalence of schizophrenia is estimated to be about 3/1000 individuals4,5. Advances in genetics of schizophrenia research have established the significance of genes in aetiology, but have not identified the main relationship between observed genetic risks and specific DNA variants, protein alterations or biological processes.

Item Type: Article
Additional Information: Unmapped bibliographic data: U1 - IJMR-140-713[PII] [Field not mapped to EPrints] U1 - 25758569[pmid] [Field not mapped to EPrints] DB - PMC [Field not mapped to EPrints] AN - PMC4365344 [Field not mapped to EPrints] J1 - Indian J Med Res [Field not mapped to EPrints]
Subjects: Agriculture Biological Sciences > Zoology
University of Mysore > PG Campuses > Manasagangotri, Mysore > Agriculture Biological Sciences > Zoology
Divisions: PG Campuses > Manasagangotri, Mysore > Zoology
Depositing User: Praveen Kumari B.L
Date Deposited: 18 May 2015 05:30
Last Modified: 15 Oct 2015 07:44
URI: http://eprints.uni-mysore.ac.in/id/eprint/17878

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