Synthesis and crystal structure of topiramate azido­sulfate at 90 K and 298 K

Priyanka, P. and Jayanna, B. K. and Kiran Kumar, H. and Vinaya and Divakara, T. R. and Yathirajan, H. S. and Glidewell, Christopher and Parkin, Sean (2022) Synthesis and crystal structure of topiramate azido­sulfate at 90 K and 298 K. Acta Crystallographica Section E, 78 (10). pp. 984-988. ISSN 2056-9890

Text (Full Text) Synthesis and crystal structure of topiramate azidosulfate at.pdf - Published Version Restricted to Registered users only Download (1MB) | Request a copy

Abstract

The low (90 K) and room (298 K) temperature crystal structures of topiramate azido­sulfate [systematic name 2,3:4,5-bis-O-(1-methyl­ethyl­idene)-β-D-fructo­pyran­ose azido­sulfate], C12H19N3O8S, an inter­mediate in the synthesis of the anti-convulsant drug topiramate, are described. Topiramate azido­sulfate (I) finds use as a reference impurity standard for topiramate. A modified synthesis and some spectroscopic details are also presented.

Item Type:	Article
Uncontrolled Keywords:	topiramate azidosulfate, intermediate, anti-convulsant, crystal structure, absolute configuration
Subjects:	C Chemical Science > Chemistry
Divisions:	Department of > Chemistry
Depositing User:	C Swapna Library Assistant
Date Deposited:	01 Oct 2022 05:45
Last Modified:	01 Oct 2022 05:45
URI:	http://eprints.uni-mysore.ac.in/id/eprint/17380

Actions (login required)

View Item