Implications of phytochemicals in snakebite management: present status and future prospective

Urs, Nanjaraj A. N. and Yariswamy, M. and Joshi, Vikram and Nataraju, A. and Gowda, T. Veerabasappa and Vishwanath, B. S. (2014) Implications of phytochemicals in snakebite management: present status and future prospective. Toxin Reviews, Toxin Reviews, 33 (3). pp. 60-83. ISSN 1556-9543

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In spite of vast advances in healthcare services, treatment of snakebite still remains a challenge to medical fraternity, because of unresolved complications of severe local tissue damage and consequential physical disabilities. Though anti-venom therapy reduces mortality, is ineffective against local tissue damage. In vitro and in vivo studies demonstrated that several alkaloids, flavonoids, polyphenols, terpenoids, saponins, sterols, glycosides, etc., from herbal medicines effectively neutralized local tissue damage induced by venom toxins/enzymes. This review emphasizes the interplay of venom toxins/enzymes in local toxicity and their neutralization using phytochemicals. Further, approaches using phytochemicals and anti-venoms are reviewed for better management of snakebite.

Item Type: Article
Additional Information: Unmapped bibliographic data: M3 - doi: 10.3109/15569543.2013.854255 [Field not mapped to EPrints] JO - Toxin Reviews [Field not mapped to EPrints]
Subjects: Agriculture Biological Sciences > Biochemistry
University of Mysore > PG Campuses > Manasagangotri, Mysore > Agriculture Biological Sciences > Biochemistry
Divisions: PG Campuses > Manasagangotri, Mysore > Biochemistry
Depositing User: Praveen Kumari B.L
Date Deposited: 08 Jan 2015 05:51
Last Modified: 17 Oct 2015 05:31

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