Catalyst-free, one-pot strategy to access 3-substituted-5- amino-1,2,4-thiadiazoles in water

Chaithra, N. and Swarup, H. A. and Yatheesh, N. and Sandhya, C. N. and Mantelingu, K. and Rangappa, K. S. (2021) Catalyst-free, one-pot strategy to access 3-substituted-5- amino-1,2,4-thiadiazoles in water. Synthetic Communications, 15 (23). pp. 3610-3619.

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Official URL: https://doi.org/10.1080/00397911.2021.1986840

Abstract

A protocol has been devised for the synthesis of 3-substituted 5-amino-1,2,4-thiadiazoles utilizing isothiocyanates, amidoximes and water as an eco-friendly solvent. The strategy involves consecutive C−N and S−N bonds formation in a one-pot reaction under catalyst-free conditions. Operational simplicity, low cost, broad substrate scope and readily available starting materials are the main features of this protocol.

Item Type: Article
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: Mr Umendra uom
Date Deposited: 11 Feb 2022 05:53
Last Modified: 12 Sep 2022 09:48
URI: http://eprints.uni-mysore.ac.in/id/eprint/17002

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