Revanasiddappa, H. D. and Manju, B. (1999) Spectrophotometric determination of some antidepressant drugs using 3-methylbenzothiazolin-2-one hydrazone. European Journal of Pharmaceutical Sciences, 9 (2). pp. 221-225.
Full text not available from this repository. (Request a copy)Abstract
A sensitive spectrophotometric method for the determination of amitriptyline hydrochloride, nortriptyline hydrochloride and doxepin hydrochloride in pure and dosage forms, is described. The method is based on the oxidative coupling of the drugs with 3-methylbenzothiazolin-2-one hydrazone in the presence of iron(III) chloride in 1 M hydrochloric acid. The commonly encountered excipients and additives do not interfere with the determinations. Results of the present method are comparable with those of official methods. The new method offers the advantage of simplicity and rapidity. (C) 1999 Published by Elsevier Science B.V. All rights reserved.
| Item Type: | Article |
|---|---|
| Subjects: | C Chemical Science > Chemistry |
| Divisions: | Department of > Chemistry |
| Depositing User: | Users 23 not found. |
| Date Deposited: | 23 Jun 2021 09:14 |
| Last Modified: | 28 Nov 2022 10:53 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/16752 |
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