Spectrophotometric determination of isoniazid with sodium 1,2-naphthoquinone-4-sulphotlate and cetyltrimethyl ammonium bromide

Nagaraja, P. and Murthy, K. C. S. and Yathirajan, H. S. (1996) Spectrophotometric determination of isoniazid with sodium 1,2-naphthoquinone-4-sulphotlate and cetyltrimethyl ammonium bromide. Talanta, 43 (7). pp. 1075-1080.

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Official URL: https://doi.org/10.1016/0039-9140(95)01864-6

Abstract

A rapid, sensitive and simple spectrophotometric method is developed for the determination of isoniazid (INH) with sodium 1,2-naphthoquinone-4-sulphonate and cetyltrimethyl ammonium bromide (CTA) in alkaline medium. Beer's law is obeyed in the range of INH concentrations of 2-5.6 mu g ml(-1) at the maximum absorption of 500 nm. Sensitivity is enhanced by the addition of CTA. The method is successfully employed for the determination of INH in various pharmaceutical preparations and common excipients used as additives in pharmaceuticals do not interfere in the proposed method.

Item Type: Article
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: Users 23 not found.
Date Deposited: 22 May 2021 06:20
Last Modified: 02 Jul 2022 09:44
URI: http://eprints.uni-mysore.ac.in/id/eprint/16564

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