PAF-acether in AK-5 tumour cells

Marathe, G. K. and Krishnakantha, T. P. and D'Souza, C. J. M. (1991) PAF-acether in AK-5 tumour cells. Cell Biology International Reports, 15 (1). pp. 85-90.

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PAF-Acether fraction derived from stimulated AK-5 tumour cells, aggregated human platelets. The platelet aggregating ability increased linearly with increasing concentration of the stimulant, calcium ionophore A23187, and reached a maximum at 6 microM in 25 minutes. This factor had biological and chemical properties identical to authentic PAF-acether. Our results demonstrate that, although PAF-acether is produced mainly from pro-inflammatory cells, it appears to be produced even in tumour cells.

Item Type: Article
Subjects: C Chemical Science > Biochemistry
Divisions: Department of > Biochemistry
Depositing User: Users 23 not found.
Date Deposited: 10 May 2021 07:41
Last Modified: 01 Jun 2023 11:08

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