Effects of Dexamethasone and Gonadotropins on the Testis of the Adrenalectomized Lizard Mabuya Carinata (Schn)

Yajurvedi, H. N. and Chandramohan, K. (1994) Effects of Dexamethasone and Gonadotropins on the Testis of the Adrenalectomized Lizard Mabuya Carinata (Schn). General And Comparative Endocrinology, 93 (2). pp. 224-231.

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Abstract

The effects of gonadotropins (LH + FSH) and dexamethasone on the spermatogenic and steroidogenic activity in the adrenalectomized Mabuya carinata have been studied. Secondary spermatocytes, spermatids, and spermatozoa were absent, and there was a significant decrease in the activity levels of Δ5-3β-hydroxysteroid dehydrogenase (Δ5-3β-HSDH) and glucose-6-phosphate dehydrogenase in the adrenalectomized lizards compared with those of controls. Administration of either dexamethasone or LH + FSH to adrenalectomized lizards resulted in restoration of testicular activity as revealed by the appearance of secondary spermatocytes, spermatids, and spermatozoa and a significant increase in the activity level of Δ5-3β-HSDH compared to that of adrenalectomized lizards. The results indicate that impairment in gonadotropin secretion might be a major factor in inducing testicular regression following adrenalectomy in M. carinata.

Item Type: Article
Subjects: B Life Science > Zoology
Divisions: Department of > Zoology
Depositing User: Users 23 not found.
Date Deposited: 27 Apr 2021 10:20
Last Modified: 02 May 2021 03:39
URI: http://eprints.uni-mysore.ac.in/id/eprint/16252

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