Tetralone Esters as intermediates for the synthesis of Podophyllotoxin derivatives via Cyclopropanation of Chalcones

Nanjundaswamy, N. and Shashikanth, S. and Anjanamurthy, C. and Rai, K. M. Lokanatha (2000) Tetralone Esters as intermediates for the synthesis of Podophyllotoxin derivatives via Cyclopropanation of Chalcones. Synthetic Communications, 30 (7). pp. 1179-1191.

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Official URL: https://doi.org/10.1080/00397910008087138

Abstract

Cyclopropyl ester (8a-f) were synthesized by the cyclopropanation of chalcones (7a-e) in dry benzene using powdered sodium in 80-85% yield. Preparation of tetralone ester (4a-e), an intermediate for the synthesis of podophyllotoxin derivatives by Lewis acid (SnCl4) catalyzed cyclization of (8a-e) is also described here.

Item Type: Article
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: C Swapna Library Assistant
Date Deposited: 17 Dec 2020 10:37
Last Modified: 20 Jan 2023 07:53
URI: http://eprints.uni-mysore.ac.in/id/eprint/14211

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